Tranquilizers

It is necessary to understand that these drugs were created as “disposable” medicines. Initially, they were conceived as symptomatic remedies for the treatment of anxiety. The authors of the historically first of them – diazepam (aka valium, seduxen, relanium, sibazone, etc.) assumed that a person who suffers from excessive anxiety can take diazepam from timeRead More

Tranquilizers. Pharmacological properties, areas of improvement, Problems of safety of use

Tranquilizers (from Lat. tranquillium — “tranquility”) represent one of the most important groups of psychotropic drugs. Recently, they are increasingly called anxiolytics (from the Latin. anxius — “anxious” and Greek. lysis — “dissolution”). There are other, less common names — ataractics (from the Greek ataraxia — “equanimity”), psychosedative, anti-neurotic drugs. In the general classification ofRead More

Overview of synthetic and design dissociatives

Ketamine is the main substance, the design of analogues was taken from it. We have a separate article about K and trip reports once and twice. Ketamine hydrochloride (“Ketamine”) is widely used for medical purposes all over the world. This drug is widely used in veterinary practice, during various types of surgical interventions. The abilityRead More

4-Methylaminorex

4-methylaminorex is a chemical compound derived from aminorex. It has a structural similarity with amphetamines. It produces a psychostimulating effect and is used as a drug. It can cause a dangerous irreversible complication — pulmonary hypertension. Isomers 4-methylaminorex can exist in the form of four isomers: cis-4R,5S, cis-4S,5R, trans-4S,5S, trans-4R,5R. Mechanism of action 4-methylaminorex increasesRead More